| Date | Opponent | Location | Outcome/Time |
| 02/10/06 | Maryland | Greenville, N.C. | W, 6-1 Recap | Box Score | Listen | Gametracker |
| 02/11/06 | Maryland | Greenville, N.C. | Postponed |
| 02/12/06 | Maryland | Greenville, N.C. | L, 1-0 Recap | Box Score | Listen | Gametracker |
| 02/12/06 | Maryland | Greenville, N.C. | W, 5-4 Recap | Box Score | Listen | Gametracker |
| 02/17/06 | College of Charleston | Greenville, N.C. | 3:00 PM ET Listen | Gametracker |
| 02/18/06 | College of Charleston | Greenville, N.C. | 2:00 PM ET Listen | Gametracker |
| 02/19/06 | College of Charleston | Greenville, N.C. | 1:00 PM ET Listen | Gametracker |
| 02/21/06 | Duke | Greenville, N.C. | 3:00 PM ET Listen | Gametracker |
| 02/24/06 | Penn State | Greenville, N.C. | 5:00 PM ET Listen | Gametracker |
| 02/25/06 | UNC-Wilmington | Greenville, N.C. | 1:30 PM ET Listen | Gametracker |
| 02/26/06 | Virginia Tech | Greenville, N.C. | 1:00 PM ET Listen | Gametracker |
| 02/28/06 | Duke | Greenville, N.C. | 4:00 PM ET Listen | Gametracker |
| 03/03/06 | Stony Brook | Greenville, N.C. | 3:00 PM ET Listen | Gametracker |
| 03/04/06 | Stony Brook | Greenville, N.C. | 1:00 PM ET Listen | Gametracker |
| 03/05/06 | Stony Brook | Greenville, N.C. | 1:00 PM ET Listen | Gametracker |
| 03/08/06 | North Carolina A&T | Greenville, N.C. | 3:00 PM ET Listen | Gametracker |
| 03/10/06 | Cal St Fullerton | Fullerton, Calif. | 10:00 PM ET Listen | Gametracker |
| 03/11/06 | Cal St Fullerton | Fullerton, Calif. | 9:00 PM ET Listen | Gametracker |
| 03/12/06 | Cal St Fullerton | Fullerton, Calif. | 4:00 PM ET Listen | Gametracker |
| 03/15/06 | UNC-Wilmington | Wilmington, N.C. | 7:00 PM ET Listen | Gametracker |
| 03/17/06 | Marist | Greenville, N.C. | 7:00 PM ET Listen | Gametracker |
| 03/18/06 | Marist | Greenville, N.C. | 2:00 PM ET Listen | Gametracker |
| 03/19/06 | Marist | Greenville, N.C. | 1:00 PM ET Listen | Gametracker |
| 03/22/06 | UNC-Wilmington | Greenville, N.C. | 7:00 PM ET Listen | Gametracker |
| 03/24/06 | Rice | Houston, Texas | 8:00 PM ET Listen | Gametracker |
| 03/25/06 | Rice | Houston, Texas | 1:00 PM ET Listen | Gametracker |
| 03/26/06 | Rice | Houston, Texas | 2:00 PM ET Listen | Gametracker |
| 03/29/06 | North Carolina State | Raleigh, N.C. | 7:00 PM ET Listen | Gametracker |
| 03/31/06 | Houston | Greenville, N.C. | 7:00 PM ET Listen | Gametracker |
| 04/01/06 | Houston | Greenville, N.C. | 6:00 PM ET Listen | Gametracker |
| 04/02/06 | Houston | Greenville, N.C. | 12:00 PM ET Listen | Gametracker |
| 04/04/06 | North Carolina A&T | Greenville, N.C. | 7:00 PM ET Listen | Gametracker |
| 04/07/06 | UCF | Orlando, Fla. | 6:30 PM ET Listen | Gametracker |
| 04/08/06 | UCF | Orlando, Fla. | 6:30 PM ET Listen | Gametracker |
| 04/09/06 | UCF | Orlando, Fla. | 1:00 PM ET Listen | Gametracker |
| 04/12/06 | North Carolina State | Greenville, N.C. | 7:00 PM ET Listen | Gametracker |
| 04/14/06 | Albany | Greenville, N.C. | 7:00 PM ET Listen | Gametracker |
| 04/15/06 | Albany | Greenville, N.C. | 6:00 PM ET Listen | Gametracker |
| 04/16/06 | Albany | Greenville, N.C. | 12:00 PM ET Listen | Gametracker |
| 04/18/06 | North Carolina State | Raleigh, N.C. | 7:00 PM ET Listen | Gametracker |
| 04/21/06 | Marshall | Greenville, N.C. | 7:00 PM ET Listen | Gametracker |
| 04/22/06 | Marshall | Greenville, N.C. | 6:00 PM ET Listen | Gametracker |
| 04/23/06 | Marshall | Greenville, N.C. | 12:00 PM ET Listen | Gametracker |
| 04/28/06 | Tulane | Greenville, N.C. | 7:00 PM ET Listen | Gametracker |
| 04/29/06 | Tulane | Greenville, N.C. | 6:00 PM ET Listen | Gametracker |
| 04/30/06 | Tulane | Greenville, N.C. | 12:00 PM ET Listen | Gametracker |
| 05/05/06 | Southern Mississippi | Hattiesburg, Miss. | 7:30 PM ET Listen | Gametracker |
| 05/06/06 | Southern Mississippi | Hattiesburg, Miss. | 5:00 PM ET Listen | Gametracker |
| 05/07/06 | Southern Mississippi | Hattiesburg, Miss. | 1:00 PM ET Listen | Gametracker |
| 05/10/06 | Coastal Carolina | Greenville, N.C. | 7:00 PM ET Listen | Gametracker |
| 05/12/06 | UAB | Greenville, N.C. | 7:00 PM ET Listen | Gametracker |
| 05/13/06 | UAB | Greenville, N.C. | 6:00 PM ET Listen | Gametracker |
| 05/14/06 | UAB | Greenville, N.C. | 12:00 PM ET Listen | Gametracker |
| 05/16/06 | Coastal Carolina | Conway, S.C. | 6:00 PM ET Listen | Gametracker |
| 05/18/06 | Memphis | Memphis, Tenn. | 7:30 PM ET Listen | Gametracker |
| 05/19/06 | Memphis | Memphis, Tenn. | 3:00 PM ET Listen | Gametracker |
| 05/20/06 | Memphis | Memphis, Tenn. | 2:00 PM ET Listen | Gametracker |
| 05/24/06 | Conference USA Tournament | Houston, Texas | TBA |